منابع مشابه
Low somatomedin-C (Sm-C) concentrations measured by direct radioimmunoassay in patients with chronic renal failure.
Ten patients suffering from chronic renal failure and undergoing regular hemodialysis were tested immediately before and immediately after a 3-hour dialysis. Serum levels of immunoreactive Sm-C, estimated on unextracted non acidified serum at non equilibrium, were significantly lower than in normal controls and no consistent modifications were observed after dialysis.
متن کاملChemiluminescence immunoassay for somatomedin C in serum.
To select the best tracer for use in a competitive immunoassay, we conjugated human somatomedin C (SmC) to various chemiluminescent compounds via two different synthetic pathways. Naphthylhydrazides and arylhydrazides, used as the labels, were incorporated via their imidate or their succinimide esters. Conjugating the carboxy terminal of (amino ethyl)ethyl-isoluminol to SmC via a succinimide li...
متن کاملSomatomedin C deficiency in Asian sisters.
Two sisters of Asian origin showed typical clinical and biochemical features of primary somatomedin C (SM-C) deficiency (Laron dwarfism). Abnormalities of SM-C binding proteins were observed, one sister lacking the high molecular weight (150 Kd) protein.
متن کاملCharacterization of soft stripe-domain deformations in Sm-C and Sm-C* liquid-crystal elastomers.
The neoclassical model of Sm-C (and Sm-C*) elastomers developed by Warner and Adams predicts a class of "soft" (zero energy) deformations. We find and describe the full set of stripe domains-laminate structures in which the laminates alternate between two different deformations-that can form between pairs of these soft deformations. All the stripe domains fall into two classes, one in which the...
متن کاملAssay of somatomedin C by cartridge extraction prior to radioimmunoassay with antiserum developed against synthetic somatomedin C.
The whole molecule of human somatomedin C (SM-C) prepared by the total synthesis method was used as an antigen to produce an antiserum for a radioimmunoassay. Since plasma proteins that bind SM-C interfere with the assay, a method was developed that uses acid dissociation followed by C-2 cartridge extraction to strip SM-C from its binding proteins before assay. This assay has no cross-reactivit...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1981
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198104001-01328